Motif ID: SOX{8,9,10}.p2

Z-value: 1.434


Transcription factors associated with SOX{8,9,10}.p2:

Gene SymbolEntrez IDGene Name
SOX10 6663 SRY (sex determining region Y)-box 10
SOX8 30812 SRY (sex determining region Y)-box 8
SOX9 6662 SRY (sex determining region Y)-box 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX10chr22_-_367098140.391.4e-01Click!
SOX9chr17_+_676287720.342.0e-01Click!
SOX8chr16_+_9720640.233.9e-01Click!


Activity profile for motif SOX{8,9,10}.p2.

activity profile for motif SOX{8,9,10}.p2


Sorted Z-values histogram for motif SOX{8,9,10}.p2

Sorted Z-values for motif SOX{8,9,10}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX{8,9,10}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_128883125 2.061 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr9_+_123501186 1.387 DAB2IP
DAB2 interacting protein
chr2_-_239987557 1.240 NM_006037
HDAC4
histone deacetylase 4
chr2_+_101680594 1.193 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr7_-_27171673 1.116 NM_152739
HOXA9
homeobox A9
chr11_+_20005704 1.079 NAV2
neuron navigator 2
chr3_-_187309442 1.039 NM_004454
ETV5
ets variant 5
chr10_-_97311084 1.035 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr7_-_27171648 1.024 HOXA9
homeobox A9
chr20_-_17610828 1.010 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr7_-_27171600 0.998 HOXA9
homeobox A9
chr6_-_11340886 0.958 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr2_-_239987629 0.942 HDAC4
histone deacetylase 4
chr17_-_46479127 0.911 SPAG9
sperm associated antigen 9
chr4_-_186969041 0.901 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_40631397 0.892 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr12_+_52665196 0.874 NM_017409
HOXC10
homeobox C10
chr20_-_17610704 0.856 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr3_-_48445719 0.854 NM_002673
PLXNB1
plexin B1
chr6_-_11340869 0.852 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_+_101488380 0.847 NM_001195045
YAP1
Yes-associated protein 1
chr2_+_152900076 0.838 FMNL2
formin-like 2
chr14_-_89490780 0.826 NM_145231
EFCAB11
EF-hand calcium binding domain 11
chr2_+_176737050 0.810 NM_006898
HOXD3
homeobox D3
chr20_+_60918836 0.802 NM_001853
COL9A3
collagen, type IX, alpha 3
chr22_+_22445035 0.790 NM_005940
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr14_+_23711044 0.778 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr14_+_23008723 0.776 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr6_-_11340887 0.764 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr5_-_16989371 0.759 NM_012334
MYO10
myosin X
chr4_-_7991992 0.758 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr22_+_31527678 0.746 TIMP3
TIMP metallopeptidase inhibitor 3
chr7_+_134114912 0.744 CALD1
caldesmon 1
chr1_-_203557379 0.743 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr13_+_97593469 0.740 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr9_+_27099138 0.733 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr8_-_29262240 0.728 NM_057158
DUSP4
dual specificity phosphatase 4
chr21_+_17807167 0.727 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr17_-_36996611 0.726 NM_000526
KRT14
keratin 14
chrX_+_67965517 0.719 NM_004429
EFNB1
ephrin-B1
chr3_+_189425886 0.714 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr17_-_1478293 0.706 SLC43A2
solute carrier family 43, member 2
chr7_+_29486010 0.698 NM_001039936
CHN2
chimerin (chimaerin) 2
chr7_-_111633428 0.698 DOCK4
dedicator of cytokinesis 4
chr13_+_112704077 0.697 MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_-_57600564 0.694 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_-_186969202 0.693 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr10_+_104253716 0.683 SUFU
suppressor of fused homolog (Drosophila)
chr3_+_189354167 0.682 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_-_11399776 0.676 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chrX_+_18353623 0.673 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr14_-_70345485 0.672 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr11_-_128567302 0.671 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr2_-_207739815 0.664 KLF7
Kruppel-like factor 7 (ubiquitous)
chr10_+_71482542 0.660 H2AFY2
H2A histone family, member Y2
chr8_+_26491317 0.655 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr10_+_73393998 0.650 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr16_-_49205063 0.648


chr1_+_15957832 0.645 NM_017556
FBLIM1
filamin binding LIM protein 1
chr8_+_26491383 0.631 DPYSL2
dihydropyrimidinase-like 2
chr6_+_148705421 0.630 NM_015278
SASH1
SAM and SH3 domain containing 1
chr5_-_50714836 0.629 LOC642366
hypothetical LOC642366
chr8_-_38444982 0.629 FGFR1
fibroblast growth factor receptor 1
chr5_+_60276695 0.622 NM_174889
NDUFAF2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
chr16_-_52877868 0.618 NM_024336
IRX3
iroquois homeobox 3
chr6_+_114285209 0.617 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr4_-_184478920 0.616 NM_001111319
CLDN22
claudin 22
chr22_+_31527744 0.615 TIMP3
TIMP metallopeptidase inhibitor 3
chr2_-_96769502 0.613 LMAN2L
lectin, mannose-binding 2-like
chr1_-_2451543 0.611 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr13_-_32658215 0.610 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_195336625 0.610 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr14_+_85066265 0.608 FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_-_94475504 0.608 ARHGAP29
Rho GTPase activating protein 29
chr3_+_112743729 0.608 CD96
CD96 molecule
chr9_-_35818728 0.604 NM_001012446
C9orf128
chromosome 9 open reading frame 128
chr8_-_38445272 0.602 FGFR1
fibroblast growth factor receptor 1
chr10_+_71482362 0.601 NM_018649
H2AFY2
H2A histone family, member Y2
chr1_-_50661716 0.593 NM_032110
DMRTA2
DMRT-like family A2
chr2_+_236068029 0.583 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr11_+_60448487 0.581 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr11_+_36274300 0.581 NM_001160167
PRR5L
proline rich 5 like
chr10_+_24538094 0.580 KIAA1217
KIAA1217
chr10_+_24537725 0.578 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr14_-_102045849 0.577 NM_152326
ANKRD9
ankyrin repeat domain 9
chr1_+_26376560 0.576 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr12_-_6103945 0.576 NM_000552
VWF
von Willebrand factor
chr6_+_17390910 0.576 NM_153020
RBM24
RNA binding motif protein 24
chr2_-_96769526 0.576 NM_001142292
NM_030805
LMAN2L

lectin, mannose-binding 2-like

chr8_+_124032830 0.575 ZHX2
zinc fingers and homeoboxes 2
chr8_-_119192985 0.570 NM_000127
EXT1
exostosin 1
chr15_+_37660568 0.569 NM_003246
THBS1
thrombospondin 1
chr10_+_104253706 0.562 NM_001178133
NM_016169
SUFU

suppressor of fused homolog (Drosophila)

chr15_-_84139182 0.562 NM_022480
KLHL25
kelch-like 25 (Drosophila)
chr7_-_27186400 0.562 NM_153715
HOXA10
homeobox A10
chr15_+_97009194 0.559 IGF1R
insulin-like growth factor 1 receptor
chr15_-_84139021 0.556 KLHL25
kelch-like 25 (Drosophila)
chr20_-_3696344 0.556 NM_001039140
C20orf27
chromosome 20 open reading frame 27
chr4_-_110942576 0.555 CFI
complement factor I
chr9_-_4142182 0.552 NM_152629
GLIS3
GLIS family zinc finger 3
chr16_-_52877829 0.548 IRX3
iroquois homeobox 3
chr4_+_78298326 0.545 CCNG2
cyclin G2
chr20_+_41519947 0.544 SRSF6
serine/arginine-rich splicing factor 6
chr11_+_75106512 0.543 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr2_-_164300758 0.540 NM_018086
FIGN
fidgetin
chr2_-_21106291 0.536 APOB
apolipoprotein B (including Ag(x) antigen)
chr12_+_62524778 0.535 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr3_-_150422474 0.534 NM_000096
CP
ceruloplasmin (ferroxidase)
chr14_-_102045749 0.532 ANKRD9
ankyrin repeat domain 9
chr7_+_148613304 0.530 LOC155060
AI894139 pseudogene
chr4_-_170314382 0.525 SH3RF1
SH3 domain containing ring finger 1
chr7_+_134114957 0.523 CALD1
caldesmon 1
chr1_-_202730135 0.518 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr2_-_215953818 0.517 FN1
fibronectin 1
chr9_+_115303527 0.517 NM_130795
RGS3
regulator of G-protein signaling 3
chr17_+_18069593 0.516 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr14_-_23090606 0.513 NM_033400
ZFHX2
zinc finger homeobox 2
chr15_+_83724743 0.511 NM_006738
NM_007200
AKAP13

A kinase (PRKA) anchor protein 13

chr10_+_24795446 0.509 KIAA1217
KIAA1217
chr5_+_50714996 0.509 ISL1
ISL LIM homeobox 1
chr17_+_39778191 0.506 GRN
granulin
chr14_-_93859394 0.505 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr1_-_95165089 0.505 NM_001839
CNN3
calponin 3, acidic
chr6_+_17390273 0.502 NM_001143941
RBM24
RNA binding motif protein 24
chr3_-_124821868 0.501 MYLK
myosin light chain kinase
chr17_-_1478859 0.500 NM_152346
SLC43A2
solute carrier family 43, member 2
chr3_-_151171576 0.497 PFN2
profilin 2
chr8_+_26491507 0.495 DPYSL2
dihydropyrimidinase-like 2
chr20_-_13919256 0.494 NM_025229
SEL1L2
sel-1 suppressor of lin-12-like 2 (C. elegans)
chr4_-_110942783 0.490 NM_000204
CFI
complement factor I
chr14_+_23008742 0.489 NGDN
neuroguidin, EIF4E binding protein
chr19_-_5291700 0.488 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr11_-_27450808 0.486 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr12_-_10142779 0.484 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr22_-_41672990 0.480 NM_007229
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr13_+_97593711 0.479 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr17_-_10393664 0.478 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr9_+_80101810 0.476 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr6_-_80001116 0.471 NM_004242
NM_138730
HMGN3

high mobility group nucleosomal binding domain 3

chr9_+_136358145 0.469 RXRA
retinoid X receptor, alpha
chr13_-_32678142 0.467 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr11_-_74914514 0.466 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr15_-_68781662 0.465 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr12_-_11439752 0.461 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr14_-_92284626 0.460 NM_001008530
NM_005606
LGMN

legumain

chr18_+_7936885 0.456 PTPRM
protein tyrosine phosphatase, receptor type, M
chr1_-_95165037 0.451 CNN3
calponin 3, acidic
chr11_+_4617520 0.451 NM_001004751
OR51D1
olfactory receptor, family 51, subfamily D, member 1
chr10_+_24795465 0.447 KIAA1217
KIAA1217
chr17_+_39778180 0.447 GRN
granulin
chr2_-_239988269 0.443 HDAC4
histone deacetylase 4
chr5_+_50714714 0.442 NM_002202
ISL1
ISL LIM homeobox 1
chr1_+_33494745 0.441 NM_152493
ZNF362
zinc finger protein 362
chr7_+_96473225 0.440 NM_005222
DLX6
distal-less homeobox 6
chr1_-_85703198 0.439 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr13_-_40138607 0.437 NM_002015
FOXO1
forkhead box O1
chr12_-_57600336 0.436 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_-_125958503 0.433 NM_001182
ALDH7A1
aldehyde dehydrogenase 7 family, member A1
chr14_+_23710924 0.427 REC8
REC8 homolog (yeast)
chr3_-_71625318 0.426 FOXP1
forkhead box P1
chr3_+_195336631 0.425 HES1
hairy and enhancer of split 1, (Drosophila)
chr4_-_5941043 0.424 CRMP1
collapsin response mediator protein 1
chr6_-_110843432 0.423 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr17_-_71017509 0.422 NM_001142643
CASKIN2
CASK interacting protein 2
chr2_-_1727220 0.422 PXDN
peroxidasin homolog (Drosophila)
chr19_-_63205948 0.419 ZNF606
zinc finger protein 606
chr2_+_228386800 0.404 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr17_-_59818033 0.403 PECAM1
platelet/endothelial cell adhesion molecule
chr19_-_10352212 0.402 NM_003331
TYK2
tyrosine kinase 2
chr18_-_72857665 0.402 MBP
myelin basic protein
chr7_-_41709191 0.397 NM_002192
INHBA
inhibin, beta A
chr10_-_105835525 0.397 COL17A1
collagen, type XVII, alpha 1
chr17_-_37196463 0.395 NM_002230
NM_021991
JUP

junction plakoglobin

chr11_-_116213511 0.390 NM_000039
APOA1
apolipoprotein A-I
chr17_+_39778153 0.390 GRN
granulin
chr19_-_10352172 0.389 TYK2
tyrosine kinase 2
chr10_-_103864651 0.389 NM_003893
LDB1
LIM domain binding 1
chr22_+_36422940 0.388 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr19_+_7566698 0.384 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr1_+_176577228 0.383 NM_004841
RASAL2
RAS protein activator like 2
chr2_+_219532590 0.383 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr2_+_74734861 0.382 NM_004263
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr13_+_28900776 0.379 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr22_-_29052863 0.379 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr13_+_97593411 0.373 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr2_-_204108151 0.373 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr4_-_186815116 0.373 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr16_-_70168449 0.373 NM_000353
TAT
tyrosine aminotransferase
chr9_-_73573121 0.371 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr15_-_53822468 0.370 NM_173814
PRTG
protogenin
chr5_-_147142249 0.367 JAKMIP2
janus kinase and microtubule interacting protein 2
chr8_+_70541412 0.367 NM_001128204
NM_015170
SULF1

sulfatase 1

chr6_+_37895244 0.364 NM_021943
ZFAND3
zinc finger, AN1-type domain 3
chr16_+_464844 0.360 NM_001142272
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr10_+_5126589 0.360 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr16_-_30705707 0.360 NM_001080417
ZNF629
zinc finger protein 629
chr8_+_70541631 0.358 SULF1
sulfatase 1
chr2_-_175337386 0.356 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr10_+_5126613 0.354 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_+_37373195 0.353



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.51 3.19e-06 GO:0007399 nervous system development
1.17 8.04e-06 GO:0050789 regulation of biological process
1.18 8.71e-06 GO:0050794 regulation of cellular process
1.28 9.22e-06 GO:0032502 developmental process
1.16 1.42e-05 GO:0065007 biological regulation
1.30 1.63e-05 GO:0007275 multicellular organismal development
1.31 2.95e-05 GO:0048856 anatomical structure development
1.92 1.10e-04 GO:0007409 axonogenesis
1.28 2.02e-04 GO:0016043 cellular component organization
2.01 2.61e-04 GO:0007411 axon guidance
1.80 4.23e-04 GO:0048858 cell projection morphogenesis
1.85 4.70e-04 GO:0048812 neuron projection morphogenesis
1.85 4.88e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.44 6.11e-04 GO:0009966 regulation of signal transduction
1.78 6.17e-04 GO:0032990 cell part morphogenesis
1.58 6.24e-04 GO:0048699 generation of neurons
1.29 7.45e-04 GO:0048731 system development
2.02 1.29e-03 GO:0030029 actin filament-based process
1.25 1.41e-03 GO:0071840 cellular component organization or biogenesis
1.54 1.68e-03 GO:0022008 neurogenesis
1.30 1.88e-03 GO:0071842 cellular component organization at cellular level
1.75 2.37e-03 GO:0000904 cell morphogenesis involved in differentiation
1.65 2.55e-03 GO:0032989 cellular component morphogenesis
1.85 2.74e-03 GO:0007264 small GTPase mediated signal transduction
1.67 2.84e-03 GO:0000902 cell morphogenesis
1.63 4.74e-03 GO:0030030 cell projection organization
1.72 5.86e-03 GO:0031175 neuron projection development
1.18 7.46e-03 GO:0032501 multicellular organismal process
1.55 1.01e-02 GO:0007155 cell adhesion
1.55 1.01e-02 GO:0022610 biological adhesion
1.31 1.06e-02 GO:0048869 cellular developmental process
1.08 1.12e-02 GO:0009987 cellular process
1.80 1.29e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.99 1.32e-02 GO:0030036 actin cytoskeleton organization
1.31 1.63e-02 GO:0030154 cell differentiation
1.57 1.73e-02 GO:0030182 neuron differentiation
1.37 1.94e-02 GO:0009653 anatomical structure morphogenesis
1.26 2.30e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.28 3.06e-02 GO:0042221 response to chemical stimulus
1.43 3.33e-02 GO:0022607 cellular component assembly
1.19 3.40e-02 GO:0051716 cellular response to stimulus
1.48 3.51e-02 GO:0040011 locomotion
4.05 4.00e-02 GO:0010811 positive regulation of cell-substrate adhesion
1.22 4.45e-02 GO:0007165 signal transduction
2.14 4.76e-02 GO:0030155 regulation of cell adhesion

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 4.61e-07 GO:0044424 intracellular part
1.10 5.17e-07 GO:0005622 intracellular
1.12 5.00e-06 GO:0043229 intracellular organelle
1.12 5.91e-06 GO:0043226 organelle
1.43 3.34e-05 GO:0005856 cytoskeleton
1.18 1.16e-04 GO:0005634 nucleus
1.67 1.87e-04 GO:0030054 cell junction
1.12 5.12e-04 GO:0005737 cytoplasm
1.12 5.15e-04 GO:0043231 intracellular membrane-bounded organelle
2.16 5.78e-04 GO:0005911 cell-cell junction
1.12 6.45e-04 GO:0043227 membrane-bounded organelle
2.15 4.82e-03 GO:0070161 anchoring junction
2.10 5.08e-03 GO:0031252 cell leading edge
1.23 1.71e-02 GO:0043228 non-membrane-bounded organelle
1.23 1.71e-02 GO:0043232 intracellular non-membrane-bounded organelle
2.35 1.85e-02 GO:0030055 cell-substrate junction
5.91 2.05e-02 GO:0043034 costamere
1.77 2.15e-02 GO:0015629 actin cytoskeleton
2.11 2.22e-02 GO:0005912 adherens junction
2.48 3.27e-02 GO:0043296 apical junction complex
1.75 3.59e-02 GO:0005874 microtubule
1.37 3.99e-02 GO:0044430 cytoskeletal part
2.92 4.64e-02 GO:0031983 vesicle lumen
2.80 4.96e-02 GO:0031091 platelet alpha granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.82 5.89e-06 GO:0008092 cytoskeletal protein binding
1.15 5.61e-05 GO:0005515 protein binding
1.08 1.57e-04 GO:0005488 binding
1.52 2.29e-04 GO:0001071 nucleic acid binding transcription factor activity
1.52 2.29e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.57 8.16e-04 GO:0019899 enzyme binding
1.83 4.21e-03 GO:0003779 actin binding
1.26 1.99e-02 GO:0003677 DNA binding